Case of how high blood pressure gout govern?

Question
Case of how high blood pressure gout govern?
Answer
Mr. Lin opened two companies, as well-run, rolling in wealth. Can fly in the ointment is that Choi made, people are quot;madequot; a:婊¢潰绾㈠厜, potbellied, weight beyond the normal standards of more than thirty kilograms. To the hospital for a check, ho, had quot;rich man#39;s diseasequot;: high blood pressure and gout. Mr. Lin鑷繓: two diseases together to it does not matter, or take care of the old methods of the two companies, go hand in hand, divide and rule. Thus, the first hospital in the city of gout, taking several drugs; hospitals in the city center to see high blood pressure, and take several drugs, taking time to go home. At the same time, get rid of cigarettes, away from the wine and reduce out entertainment, the wholeDiet surface. Also allows the Secretary of the daily blood pressure measurement to their own, sooner or later, the first time. And so it goes, two months, blood pressure gradually decreased. Mr. Lin, the hearts of a happy, to the Secretary of a red envelope. However, a meeting that evening to return home soon鐫'笅, we feel that pain right foot. Turn on the lights look red and swollen toe joints. Attack of gout and Mr. Lin are wondering: I have been gout medicine service, how not effective in gout specialist, Professor Mr. Lin asked in detail about the incidence and treatment of back and forth for some, but also did some checking, and finally told him that The attack of gout may be caused by blood pressure lowering drugs. The fundamental pathogenesis of goutThe reason is that as a result of enzyme deficiencies in some patients, so that purine metabolic abnormalities, generate too much uric acid. Low solubility of urate in the blood than normal, at too saturated, resulting in minor urate crystal deposition in the synovium, causing aseptic inflammation, pain-induced. Some blood pressure drugs may prevent the excretion of uric acid, resulting in elevated blood uric acid, is the most common diuretics. It is the step-down principle of sodium from the body to remove water, reducing blood volume and lower blood pressure; In addition, in vivo less sodium into the cells of calcium also reduced, to expand blood vessels, decrease blood pressure. ButLong-term use of diuretics may prevent the excretion of uric acid from the kidneys, blood concentration, lead to hyperuricemia or gout attack. Mr. Lin said: quot;The two diseases have, however, press the gourd dipper float, what to do? Whether diuretics stopped this.quot; The old professor said: While the new antihypertensive agents have emerged, but the World Health Organization International Society of Hypertension and diuretics are still recommended as the most valuable antihypertensive agents, because it can use low-dose effect, but also cheap. New standard treatment of hypertension that the majority of hypertensive patients taking at least two antihypertensive drugs to reduce the risk of complications of other diseases, in which theIs a diuretic. Mr. Lin said: quot;The suspension can not stop, and do not use, really makes the dilemma.quot; Professor comfort him not to worry, this situation is often encountered clinically, there are ways to deal with. Caused by elevated blood uric acid drugs are potassium-based scheduling, or sodium in the row, but also the promotion of exclusive potassium, should not be long-term use, can be used K-type diuretics security, such as spironolactone, triamterene HD-H, Hartley acid, uric acid, such as Lee indanone. Both of these drugs antihypertensive diuretic and can reduce the serum uric acid. Acetazolamide also alkalization of urine, an increase from the role of uric acid. After listening to Mr. Lin is happy, even said: quot;such a good medicine! Taking care of both sides, kill two birds with one. quot;Old professor said:quot; I have not finished it. More types of antihypertensive drugs, there are two types of antihypertensive drugs, calcium blockers, and 尾 1 receptor blockers, it will also impede the renal excretion of uric acid, increased serum uric acid concentration, induce or aggravate gout. However, different species of the impact of serum uric acid vary greatly. Calcium blocker nifedipine (nifedipine) and a 尾-blocker propranolol in (propranolol) after long-term use may cause increased serum uric acid; and the same calcium blocker Norvasc (amlodipine), and with a 尾-blocker for the Betaloc (metoprolol) on uric acid filmRing is very minor. Now, I look to you to adjust the treatment program, you can also control blood pressure and uric acid, will not come to #39;press the gourd dipper float#39; the. quot;Mr. Lin said:quot; Thank you. The next doctor, I would like to see the two diseases together so that doctors take into consideration. quot;(Editor: Wang Hai-e)
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